What is Synvisc One?
Synvisc One is a highly viscous hyaluronic acid joint injection for the treatment of knee osteoarthritis. The decisive advantage: Just a single injection is necessary to achieve up to 6 months of pain relief - thanks to the special Hylan G-F 20 polymer.
With 48 mg of Hylan polymer in a 6 ml volume, Synvisc One offers a particularly high viscosity and therefore intensive, long-lasting joint lubrication especially for the knee joint.
💡 Special advantage
Only ONE injection with Hylan polymer - highest viscosity for intensive joint lubrication and up to 6 months of effect.
What is Hylan G-F 20 and why is it special?
Synvisc One contains Hylan G-F 20, a specially developed hyaluronic acid polymer with unique properties:
1. Highest viscosity
Hylan G-F 20 is a cross-linked hyaluronic acid polymer with significantly higher viscosity than standard hyaluronic acid. This results in more intense and longer-lasting joint lubrication.
2. Longer stay in the joint
Thanks to its polymer structure, Hylan G-F 20 remains in the knee joint longer than conventional hyaluronic acid. This enables an effect of up to 6 months with just one injection.
3. Better shock absorption
The high viscosity ensures superior shock absorption and protects the cartilage more effectively from mechanical stress.
4. Clinically proven
Synvisc One from Sanofi-Aventis has been clinically proven for many years and is used by orthopedic surgeons worldwide for knee osteoarthritis.
How does Synvisc One work for knee osteoarthritis?
Synvisc One unfolds its effect on several levels thanks to the highly viscous Hylan polymer:
Intensive joint lubrication
The Hylan polymer acts as a particularly effective lubricant and reduces friction between the joint surfaces significantly more than standard hyaluronic acid.
Superior shock absorption
Synvisc One forms a highly viscous protective layer in the knee joint and acts as an intensive shock absorber. The cartilage is optimally protected from stress.
Anti-inflammatory
The Hylan polymer inhibits inflammatory processes in the knee joint and leads to a significant reduction in pain.
Long-lasting effect
Because it remains in the joint for a longer period of time, Synvisc One offers an effective duration of up to 6 months - with just a single injection.
Synvisc One vs. standard hyaluronic acid
Who is Synvisc One suitable for?
Synvisc One is specifically developed for:
- Knee osteoarthritis (gonarthrosis) – primary indication
- Patients who only want one injection
- Mild to moderate knee osteoarthritis
- Chronic knee pain despite conservative therapy
- Limited mobility of the knee joint
- Insufficient effect of painkillers
- Desire for non-surgical treatment
- Bridging the gap until the planned knee operation
⚠️ Important to know:
Synvisc One is specifically approved for the knee joint. Other hyaluronic acid preparations should be used for other joints (hips, shoulders).
Who particularly benefits from Synvisc One?
Synvisc One is the ideal choice for patients who:
- Want just a single injection (instead of multiple treatments)
- Require maximum viscosity and intensive joint lubrication
- Suffer from moderate knee osteoarthritis
- Looking for long-lasting pain relief
- Prefer fewer doctor visits
- Want a proven brand from Sanofi-Aventis
Treatment process: This is how the Synvisc One injection works
Before treatment
Your doctor will examine your knee joint and determine whether Synvisc One is suitable for you. In the case of acute inflammation or infection, treatment should be postponed.
Treatment regimen
The big advantage of Synvisc One:
- Just ONE injection required
- No weekly follow-up treatments necessary
- Maximum comfort and time savings
- Immediately complete dosage in the knee joint
During the injection
- Disinfection: The knee joint is thoroughly disinfected
- Anesthesia (optional): If necessary, local anesthesia of the injection site
- Injection: The 6 ml Hylan polymer solution is precisely injected into the joint space
- Duration: The entire treatment only takes a few minutes
After treatment
- Protection of the knee joint for 48 hours
- Avoid heavy exertion, jogging and sports
- Light exercise and walking are permitted and beneficial
- The first improvements are usually noticeable after 1-2 weeks
- Maximum effect after 4-8 weeks
- Effect lasts up to 6 months
Scientific evidence and study situation
The effectiveness of Synvisc One has been proven by numerous clinical studies. Patients report:
- Significant pain reduction by an average of 40-60%
- Improved knee function and mobility
- Longer duration of action through Hylan polymer
- Increased quality of life in everyday life
- Reduced need for painkillers
- Delaying knee surgeries
- High patient satisfaction through a single injection
Synvisc One is manufactured by Sanofi-Aventis and has been used worldwide for many years.
Frequently asked questions about Synvisc One
How long does Synvisc One last?
The effect usually lasts up to 6 months. Many patients report pain relief for 6-9 months. The duration of action depends on the severity of the knee osteoarthritis.
How many injections do I need?
Only ONE injection per treatment cycle – that is the big advantage of Synvisc One. No weekly follow-up treatments required.
What is the difference from normal Synvisc?
Synvisc One contains the entire dose in a single 6ml injection, while regular Synvisc requires 3 injections of 2ml over 3 weeks. Both contain the same Hylan G-F 20.
Is the treatment painful?
The injection may be briefly uncomfortable. The larger volume (6 ml) can cause a greater feeling of pressure than with smaller injections. Local anesthesia is possible if desired.
When does the effect occur?
The first improvements are usually noticeable after 1-2 weeks. The maximum effect occurs after 4-8 weeks.
Can I repeat the treatment?
Yes, the treatment can be repeated without any problems after 6-12 months. Many patients undergo regular treatment in order to remain permanently pain-free.
Can Synvisc One be injected into other joints?
Synvisc One is specifically approved for the knee joint. Other hyaluronic acid preparations should be used for hips, shoulders or other joints.
Does the health insurance company cover the costs?
The cost coverage varies depending on the health insurance company and individual situation. Talk to your doctor and your health insurance company about the options.
Are there any side effects?
Synvisc One is well tolerated. Possible side effects include:
- Swelling or feeling of pressure in the knee (1-3 days)
- Temporary redness at the injection site
- Joint effusion (rare, usually self-limiting)
- Mild pain after injection
Technical data: Synvisc One 48 mg / 6 ml
Storage and shelf life
- Store at room temperature (below 25°C).
- Protect from direct sunlight
- Do not freeze
- Store in original packaging
- Note shelf life (see packaging)
Scope of delivery
- 1 pre-filled syringe of 6 ml (48 mg Hylan G-F 20)
- 1 sterile injection cannula
- Package leaflet with detailed application information
- Certificate of Conformity
Order Synvisc One now
Just one injection of Hylan polymer for up to 6 months of pain relief
To the product →Conclusion: Why Synvisc One is the best choice for knee osteoarthritis
Synvisc One impresses with its unique combination of:
- ✅ Just one injection instead of multiple treatments
- ✅ Hylan G-F 20 polymer with the highest viscosity
- ✅ Long-lasting effect up to 6 months
- ✅ Intensive joint lubrication especially for the knee joint
- ✅ Clinically proven for many years
- ✅ Fewer doctor visits and maximum comfort
- ✅ Manufactured by Sanofi-Aventis in Germany
If you suffer from knee osteoarthritis and are looking for an effective one-time treatment with maximum viscosity, Synvisc One is an excellent choice. Talk to your doctor about the options for Synvisc One treatment.
📦 Order Synvisc One now
Synvisc One 48 mg / 6 ml pre-filled syringe
✓ Available immediately
✓ Original from the manufacturer Sanofi-Aventis
✓ Made in Germany
✓ With Hylan G-F 20 polymer
✓ Only 1 injection required
✓ Includes sterile injection cannula