Belotero 2026: The complete guide for professionals

Belotero from Merz Aesthetics is one of the leading hyaluronic acid fillers worldwide and is characterized by its unique CPM technology (Cohesive Polydensified Matrix) out. This enables particularly even integration into the skin and natural results without the Tyndall effect.

The Belotero product family at a glance

1. Belotero Soft – For the finest lines

Product features:

• Concentration: 20 mg/ml hyaluronic acid
• Viscosity: Low
• Injection Depth: Superficial (upper to middle dermis)
• Shelf life: 6-9 months
• Available: With lidocaine and without lidocaine

Main indications:

• Fine perioral lines (smoker's wrinkles)
• Crow's feet (lateral eye wrinkles)
• Fine forehead wrinkles
• Superficial skin structure improvement
• Tear trough (for thin skin)

2. Belotero Balance – The all-rounder

Product features:

• Concentration: 22.5 mg/ml hyaluronic acid
• Viscosity: Medium
• Injection depth: Middle dermis
• Shelf life: 9-12 months
• Available: With lidocaine and without lidocaine

Main indications:

• Nasolabial folds (mild to moderate)
• Marionette wrinkles
• Lip contouring
• Moderate forehead wrinkles
• Glabellar wrinkles (frown lines)
• Mentolabial fold (chin-lip fold)

Special feature: Balance is the most versatile product in the Belotero range and is suitable for most aesthetic indications.

3. Belotero Intense – For deep wrinkles

Product features:

• Concentration: 25 mg/ml hyaluronic acid
• Viscosity: High
• Injection depth: deep dermis to subcutis
• Shelf life: 12-15 months
• Available: With lidocaine and without lidocaine

Main indications:

• Deep nasolabial folds
• Pronounced marionette wrinkles
• Lip volume (moderate augmentation)
• Deep glabellar wrinkles
• Cheek contouring (light)

4. Belotero Volume – For structural volume building

Product features:

• Concentration: 26 mg/ml hyaluronic acid with lidocaine
• Viscosity: Very high
• Injection depth: subcutaneous to supraperiosteal
• Shelf life: 12-18 months
• Available: 2 x 1 ml with lidocaine and 2 x 1ml

Main indications:

• Cheek structure and midface volume
• Chin augmentation
• Jaw contouring (Jawline)
• Temple region (Temporal Hollowing)
• Back of hand volumization

CPM technology: The Belotero unique selling point

The Cohesive Polydensified Matrix (CPM) Technology distinguishes Belotero from other hyaluronic acid fillers:

Advantages of CPM technology:

• Uniform integration: The HA molecules are networked in such a way that they integrate optimally into the skin structure
• No Tyndall effect: No bluish discoloration even after superficial injection
• Natural results: Soft, natural-looking corrections without visible edges
• High formability: Can still be modeled after injection
• Low tendency to swelling: Minimal water intake reduces postoperative swelling

Product comparison: Which Belotero for which application?

Injection techniques for optimal results

General principles:

• Slow injection: Max. 0.1 ml per second for even distribution
• Aspiration: Before each injection to exclude intravascular placement
• Massage: Gentle modeling immediately after injection
• Layered structure: Multiple thin layers instead of one thick one

Product-specific techniques:

Belotero Soft:

• Technique: Serial Puncture or Linear Threading
• Needle: 30G or 32G
• Angle: 10-15° to the skin surface
• Tip: Inject very superficially, tense the skin slightly

Belotero Balance:

• Technique: Linear Threading, Fanning or Serial Puncture
• Needle: 27G-30G or blunt cannula 25G
• Angle: 30-45° to the skin surface
• Tip: Versatile, good for beginners

Belotero Intense:

• Technology: Linear Threading, Depot or Fanning
• Needle: 27G or blunt cannula 23G-25G
• Angle: 45° to the skin surface
• Tip: Inject deeper for optimal lifting

Belotero Volume:

• Technique: bolus, depot or blunt cannula
• Needle: 25G-27G or blunt cannula 22G-23G
• Angle: Vertical or 45° depending on the area
• Tip: Supraperiosteal for structural construction

Treatment protocol

Before treatment:

1. Medical history: check allergies, previous treatments, medications
2. Photo documentation from multiple perspectives
3. Information about risks, side effects, alternatives
4. Obtain written informed consent
5. Thorough disinfection of the treatment area
6. Topical anesthesia or dental block (optional)

During treatment:

1. Mark treatment areas with a pen
2. Choose the right Belotero product
3. Inject slowly and in a controlled manner
4. Gentle massage for shaping
5. Carry out symmetry check
6. Correct if necessary

After treatment:

1. Cooling for 10-15 minutes to reduce swelling
2. Provide aftercare instructions in writing
3. Photo documentation immediately after treatment
4. Arrange a follow-up check after 2 weeks

Patient education

Before treatment avoid:

• Stop taking blood-thinning medications 7 days in advance (after consulting a doctor)
• Avoid alcohol 24 hours beforehand
• Pause vitamin E and omega-3 supplements 1 week beforehand
• No dental treatments 2 weeks before/after lip treatment

After treatment avoid:

• 24 hours: No make-up, no intensive facial cleansing
• 48 hours: No intense physical activity, no alcohol
• 1 week: No sauna, solarium, extreme heat or cold
• 2 weeks: No facial treatments (peels, lasers)
• 4 weeks: No dental treatment for lip augmentation

Normal side effects (temporary):

• Redness and swelling (1-3 days)
• Tenderness (3-7 days)
• Minor bruising (3-10 days)
• Slight asymmetry (can be corrected)

Safety and complication management

Risk zones and vascular courses:

Be particularly careful with:

• Glabellar region: Supratrochlear artery, nasal dorsal artery
• Nasolabial fold: Angular artery, facial artery
• Tear trough: Infraorbital artery
• Lips: Superior/inferior labial artery

Emergency management of vascular occlusion:

1. Immediately: Stop injection
2. Hyaluronidase: Inject 150-300 IU directly into affected area
3. Massage: Powerful massage to promote blood circulation
4. Heat: Apply warm compresses
5. Aspirin: 300 mg for thrombosis prophylaxis
6. Monitoring: Monitor patient closely
7. In case of deterioration: Refer to the clinic immediately

Belotero vs. competition

Belotero vs. Juvederm:

Belotero vs Restylane:

Costs and profitability

Patient prices (average DACH region):

• Nasolabial folds: 350-600 € (1-2 syringes Balance/Intense)
• Lip augmentation: 400-700 € (1-2 syringes Balance/Intense)
• Tear trough: 400-650 € (1-2 syringes Soft/Balance)
• Cheek structure: 600-1,200 € (2-4 syringes volume)
• Fine lines: 300-500 € (1 syringe soft)

Product consumption per treatment:

• Nasolabial folds: 1-2 ml (Balance or Intense)
• Lips: 0.5-2 ml (Balance or Intense)
• Tear trough: 0.5-1 ml per side (Soft or Balance)
• Cheeks: 2-4 ml total (volume)
• Chin: 1-2 ml (volume)

Storage and handling

Optimal storage conditions:

• Temperature: 2-25°C (do not freeze)
• Light: Protect from direct sunlight
• Packaging: In original packaging until use
• Durability: See expiry date (typically 2 years)

Preparation for injection:

1. Bring product to room temperature 30 minutes before use
2. Visual inspection for discoloration or particles
3. Sterile removal from the packaging
4. Choose a suitable needle or cannula

Frequently Asked Questions (FAQ)

How long do Belotero fillers last?

The shelf life varies depending on the product and treatment area: Soft 6-9 months, Balance 9-12 months, Intense 12-15 months, Volume 12-18 months. Individual factors such as metabolism and depth of injection influence the duration.

What makes Belotero different from other fillers?

The CPM technology enables particularly even integration into the skin without the Tyndall effect, even with superficial injection. This makes Belotero ideal for fine lines and natural results.

Is Belotero painful?

Most Belotero products are available with lidocaine, which makes the treatment much more pleasant. Additionally, topical anesthetic creams may be used.

Can Belotero fillers be dissolved?

Yes, Belotero can be completely dissolved with hyaluronidase. This provides peace of mind in case of unwanted results or complications.

When are results visible?

The results are visible immediately after treatment. The final result becomes apparent after swelling has subsided, typically after 1-2 weeks.

Conclusion: Belotero for natural aesthetic results

With its CPM technology, Belotero offers a unique solution for natural aesthetic corrections. The four product variants cover the entire spectrum from fine lines to structural volume building.

Main advantages of Belotero:

• No Tyndall effect, even with superficial injection
• Even integration into the skin structure
• Natural, soft results
• High formability and modelability
• Low tendency to swelling
• Reversible with hyaluronidase

Ideal for:

• Practitioners who prefer natural results
• Patients with thin skin
• Fine to moderate wrinkle treatment
• Lip treatments with natural results
• Tear trough corrections

With the right product selection, precise injection technique and in-depth anatomical knowledge, Belotero can achieve excellent aesthetic results that satisfy patients and impress them in the long term.

Belotero products at FitTec

At FitTec you will find the complete Belotero range from Merz Aesthetics:

• Belotero Soft Lidocaine 1 x 1 ml
• Belotero Balance Lidocaine 1 x 1 ml
• Belotero Intense Lidocaine 1 x 1 ml
• Belotero Volume with Lidocaine 2 x 1 ml

All products are original, certified and intended for professional medical use. Fast delivery and expert advice included.

Note: This article is intended solely for the information of healthcare professionals. All treatments should only be performed by qualified and licensed physicians. As of: January 2026