Dermal fillers have become an integral part of aesthetic medicine. But with over 20 different brands, the choice is difficult: which filler lasts the longest? Which one is best for lips? How much do the different brands cost? In this comprehensive comparison, we highlight all the top dermal filler brands and help you make the right choice.
The most important dermal filler brands at a glance
There are numerous dermal filler manufacturers on the market. The main and most commonly used brands are:
- Juvederm (Allergan/AbbVie) - global market leader
- Restylane (Galderma) - Second major brand
- Belotero (Merz Aesthetics) - German quality
- Teosyal (Teoxane) - Swiss premium brand
- Style (Vivacy) - French innovation
- Revolax (Across) - Korean quality
- Perfectha (Sinclair) - French tradition
- Princess (Croma) - Austrian brand
Durability in comparison
Durability is one of the most important criteria when choosing a derma filler. It varies depending on the product, treatment area and individual metabolism.
Shelf life by brand
Juvéderm (Vycross series): 12-24 months
- Voluma: 18-24 months (longest shelf life)
- Volift: 15-18 months
- Volbella: 12-15 months
- Volux: 18-24 months
Juvéderm (Ultra series): 6-15 months
- Ultra 2: 6-9 months
- Ultra 3: 9-12 months
- Ultra 4: 12-15 months
Restylane: 6-18 months
- Restylane Lyft: 12-18 months
- Restylane Defyne: 12-18 months
- Restylane Refyne: 9-12 months
- Restylane Kysse: 9-12 months
Belotero: 6-18 months
- Belotero Volume: 12-18 months
- Belotero Intense: 9-12 months
- Belotero Balance: 6-9 months
- Belotero Soft: 6-9 months
Teosyal: 9-18 months
- Teosyal Ultra Deep: 12-18 months
- Teosyal Deep Lines: 9-12 months
- Teosyal Kiss: 9-12 months
Style: 9-15 months
- Style XXL: 12-15 months
- Style XL: 12-15 months
- Style L: 9-12 months
Revolax: 9-18 months
- Revolax Deep: 12-18 months
- Revolax Sub-Q: 12-18 months
- Revolax Fine: 9-12 months
Perfectha: 9-15 months
- Perfectha Subskin: 12-15 months
- Perfectha Deep: 9-12 months
- Perfectha Derm: 9-12 months
Factors affecting durability
- Treatment area: Areas with a lot of movement (lips, nasolabial folds) = shorter shelf life
- Metabolism: Faster metabolism = faster breakdown
- Injection depth: Deeper injections = longer shelf life
- Product concentration: Higher HA concentration = longer shelf life
- Degree of networking: More cross-linked HA = longer shelf life
Cost comparison
Costs vary depending on brand, product line and pack size. Here is an overview of the price categories:
Premium segment
- Juvéderm Vycross series - Premium quality with longest durability
- Teosyal - Swiss precision and quality
- Restylane - Established brand with extensive research
Middle class segment
- Belotero - Excellent value for money
- Style - Innovative technology at fair prices
- Juvéderm Ultra series - Proven quality
Price-performance segment
- Revolax - Excellent value for money
- Perfectha - French quality at attractive prices
- Princess (Croma) - Solid quality, budget-friendly
Areas of application in comparison
For lips
Top recommendations:
- Juvéderm Volbella - Most natural results, long lasting
- Juvéderm Ultra Smile - specialist for lips
- Restylane Kysse - Specially developed for lips
- Teosyal Kiss - Soft consistency for natural lips
- Belotero Lips - Very natural
Also ideal for: Stylage S, Perfectha Fine, Revolax Fine
For nasolabial folds
Top recommendations:
- Juvéderm Ultra 3/4 - Proven classic
- Juvéderm Volift - Vycross technology
- Restylane Defyne - For deep wrinkles
- Belotero Intense - Excellent integration
- Teosyal Deep Lines - Especially for wrinkles
For cheeks and volume
Top recommendations:
- Juvéderm Voluma - Longest shelf life (18-24 months)
- Restylane Lyft - Strong lifting
- Teosyal Ultra Deep - High viscosity
- Stylage XXL - Maximum volume
- Revolax Sub-Q - Excellent value for money
For chin and jaw
Top recommendations:
- Juvéderm Volux - Specially developed for the chin/jaw
- Restylane Lyft - Strong contouring
- Teosyal Ultra Deep - Firm consistency
- Stylage XXL - High viscosity
For fine lines
Top recommendations:
- Belotero Soft - Very fine integration
- Belotero Balance - Natural Results
- Juvéderm Ultra 2 - Soft consistency
- Restylane Refyne - For fine wrinkles
Technology comparison
Vycross technology (Juvéderm)
Special feature: Combination of different HA molecule sizes
Strengths:
- Longer shelf life up to 24 months
- Reduced swelling
- Particularly natural results
- Excellent dimensional stability
Products: Voluma, Volift, Volbella, Volux
NASHA technology (Restylane)
Special feature: Non-Animal Stabilized Hyaluronic Acid
Strengths:
- Very pure hyaluronic acid
- Excellent tolerance
- Natural, predictable results
- Extensively researched
Products: Entire Restylane family
CPM technology (Belotero)
Special feature: Cohesive Polydensified Matrix
Strengths:
- Best skin integration on the market
- No pilling
- Even, natural distribution
- Ideal for superficial treatments
Products: Entire Belotero family
Resilient Hyaluronic Acid (Teosyal)
Special feature: Particularly resistant HA
Strengths:
- Long shelf life
- Excellent dimensional stability
- Swiss precision and quality
- Very natural results
IPN-Like Technology (Style)
Special feature: Mannitol as an antioxidant
Strengths:
- Significantly reduced swelling
- Faster healing
- Longer shelf life
- Innovative French technology
Large comparison table
| Brand | Manufacturer | Durability | price segment | Special feature | Ideal for |
|---|---|---|---|---|---|
| Juvederm Vycross | Allergan | 12-24 months | Premium | Vycross technology | Volume, long term |
| Juvederm Ultra | Allergan | 6-15 months | Means | Proven, versatile | wrinkles, lips |
| Restylane | Galderma | 6-18 months | Premium | NASHA technology | All areas |
| Belotero | Merz | 6-18 months | Means | CPM, best integration | Fine lines |
| Teosyal | Teoxanes | 9-18 months | Premium | Resilient HA | Volume, wrinkles |
| Style | Vivacy | 9-15 months | Means | Mannitol | All areas |
| Revolax | Across | 9-18 months | Budget | Price-performance | Volume |
| Perfectha | Sinclair | 9-15 months | Budget | French quality | All areas |
Special features & strengths of the top brands
Juvéderm - The world market leader
Strengths:
- World market leader with the most extensive research
- Vycross series with the longest shelf life (up to 24 months)
- Largest product range for all applications
- Particularly natural, predictable results
- Lidocaine in all products for low-pain treatment
Ideal for: All applications, especially when longer shelf life is desired
Restylane - The established alternative
Strengths:
- Second major established global brand
- NASHA technology for maximum purity
- Excellent tolerance
- Wide, specialized product range
- Long shelf life up to 18 months
Ideal for: All areas, especially for sensitive skin
Belotero - The integration specialist
Strengths:
- CPM technology for best skin integration
- Ideal for fine lines and superficial treatments
- No pilling
- Excellent value for money
- German quality from Merz Aesthetics
Ideal for: Fine lines, perioral wrinkles, natural results
Teosyal - Swiss premium quality
Strengths:
- Swiss precision and quality standards
- Resilient HA for long durability
- Very natural, elegant results
- Wide product range
- Innovative formulations
Ideal for: Sophisticated treatments, volume building
Stylage - French innovation
Strengths:
- Mannitol significantly reduces swelling
- Faster healing and less downtime
- Excellent value for money
- Innovative IPN-Like technology
- Good durability
Ideal for: Patients who want quick healing
Revolax - price-performance champion
Strengths:
- Best value for money on the market
- Excellent quality despite an attractive price
- Long shelf life up to 18 months
- Ideal for building volume
- Growing popularity worldwide
Ideal for: Volume treatments, budget-conscious practices
Perfectha - French tradition
Strengths:
- French quality and tradition
- Attractive prices
- Very good tolerance
- Natural, harmonious results
- Solid durability
Ideal for: All standard applications at fair prices
Buying advice: Which filler is the right one?
For beginners
Recommendation: Juvéderm Ultra 3, Belotero Balance, Stylage M
Why: Versatile, proven, predictable results
For maximum durability
Recommendation: Juvéderm Voluma, Juvéderm Volux, Restylane Lyft
Why: 18-24 months shelf life, fewer follow-up treatments required
For natural lips
Recommendation: Juvéderm Volbella, Restylane Kysse, Teosyal Kiss
Why: Specially developed for lips, particularly natural results
For the budget-conscious
Recommendation: Revolax, Perfectha, Stylage
Why: Excellent quality at attractive prices
For fine lines
Recommendation: Belotero Soft, Belotero Balance
Why: Best skin integration, perfect for superficial treatments
For volume building
Recommendation: Juvéderm Voluma, Teosyal Ultra Deep, Revolax Sub-Q
Why: High viscosity, strong lifting, long lasting
Frequently asked questions (FAQ)
Which dermal filler lasts the longest?
Juvéderm Voluma and Volux with a shelf life of 18-24 months. Restylane Lyft and Teosyal Ultra Deep also last 12-18 months.
Which filler is best for lips?
Juvéderm Volbella, Restylane Kysse and Teosyal Kiss are specifically designed for lips and deliver the most natural results.
Are there quality differences between expensive and cheap fillers?
All brands presented here offer high quality. The price often depends on research effort, brand awareness and special technologies. Even cheaper brands like Revolax deliver excellent results.
Can you combine different brands?
Yes, this is possible and is often done. The expertise of the practitioner is important.
Which filler for beginners?
Juvéderm Ultra 3, Belotero Balance or Stylage M - versatile, proven and with predictable results.
Conclusion: Make the right choice
All dermal filler brands presented offer high quality and excellent results. The choice depends on individual factors:
- Treatment area: Lips, cheeks, wrinkles?
- Desired durability: 6 months or 24 months?
- Budget: Premium or value for money?
- Special requirements: Fast healing? Maximum integration?
Our top recommendations:
- All-rounder: Juvederm Ultra 3
- Longest shelf life: Juvederm Voluma
- Best lips: Juvederm Volbella
- Price-performance: Revolax
- Fine lines: Belotero balance
- Premium quality: Teosyal
Let an experienced practitioner advise you on which filler is best suited to your individual needs!
Further information: