Hyaluronic acid for osteoarthritis: effect, costs & best preparations

Osteoarthritis is one of the most common joint diseases worldwide. Millions of people suffer from pain, stiffness and limited mobility. Hyaluronic acid injections have been established as an effective treatment method. In this comprehensive guide you will learn everything about osteoarthritis treatment with hyaluronic acid.

What is osteoarthritis?

Osteoarthritis is a degenerative joint disease in which the cartilage between bones gradually breaks down. This leads to pain, inflammation and limited mobility. The most commonly affected areas are the knees, hips, shoulders and finger joints.

Symptoms of osteoarthritis

  • Joint pain, especially under strain
  • morning stiffness
  • Limited mobility
  • Swelling and inflammation
  • Crunching noises in the joint

How does hyaluronic acid work on osteoarthritis?

Hyaluronic acid is a natural component of synovial fluid. In osteoarthritis, the concentration and quality of hyaluronic acid in the joint is reduced. Injections are used to replenish and improve the synovial fluid.

Mechanism of action

Hyaluronic acid injections work on several levels:

  • Joint lubrication: Improves the gliding ability of the joint surfaces
  • Shock absorption: Protects the cartilage from further wear and tear
  • Anti-inflammatory: Reduces inflammatory processes in the joint
  • Pain relief: Sustainably reduces pain
  • Cartilage protection: Can slow down cartilage breakdown

What hyaluronic acid preparations are there?

There are different hyaluronic acid preparations with different properties. The choice depends on the severity of the osteoarthritis, the affected joint and individual factors.

Standard preparations

Ostenil 20 mg: Proven standard preparation for medium joints. Usually 3-5 injections every week.

Hya-ject 20 mg: Price-performance winner with proven quality. Similar injection scheme to Ostenil.

Highly concentrated preparations

Ostenil Plus 40 mg: Higher concentration for more severe symptoms. Longer duration of action due to higher hyaluronic acid content.

Hya-ject Plus 40 mg: Highly concentrated alternative with a good price-performance ratio.

One-time injections

Durolane 60 mg: Only one injection needed. Highly cross-linked hyaluronic acid with long-term effects up to 6 months.

Synvisc One 48 mg: Single injection with Hylan polymer. Particularly established in knee osteoarthritis.

Special preparations

Ostenil Mini 10 mg: Specially developed for small joints such as fingers and toes.

Ostenil Tendon 40 mg: For tendons and tendon sheaths for tendonitis.

💡 Detailed comparison: Read ours Comprehensive hyaluronic acid injections comparison with all preparations in detail.

Treatment process: This is how the therapy works

1. Diagnosis and indications

Before treatment, a thorough examination will be carried out by the doctor. X-rays or MRI can show the severity of the osteoarthritis.

2. Injection scheme

Depending on the preparation, 1-5 injections are carried out:

  • Standard preparations: 3-5 injections at an interval of 1 week
  • One-time injections: Only 1 injection required
  • Highly concentrated preparations: 1-3 injections

3. Carrying out the injection

The injection is carried out under sterile conditions directly into the affected joint. If necessary, joint fluid can be removed beforehand. The treatment only takes a few minutes.

4. Aftercare

After the injection, the joint should be protected for 24-48 hours. Light exercise is permitted, but heavy exertion should be avoided.

Duration and repetition

The duration of action varies depending on the preparation and individual response:

  • Standard preparations: 3-6 months
  • Highly concentrated preparations: 6-9 months
  • One-time injections: 6-12 months

The treatment can be repeated if necessary. Many patients benefit from regular injections 1-2 times per year.

Which joints are suitable for?

Knee osteoarthritis

The most common application. Hyaluronic acid injections have been particularly well studied and established for knee osteoarthritis.

Hip osteoarthritis

Also effective for hip osteoarthritis, but the injection is technically more demanding and is usually carried out under ultrasound or X-ray control.

Shoulder osteoarthritis

Good results for shoulder arthrosis and frozen shoulder. Improves mobility and reduces pain.

finger joints

Also suitable for small joints with special mini preparations. Especially with thumb and saddle joint osteoarthritis.

Ankle joint

For ankle osteoarthritis following injuries or degenerative changes.

Benefits of hyaluronic acid therapy

  •  Natural active ingredient, endogenous
  •  Long-lasting pain relief
  •  Improved mobility
  •  Well tolerated with few side effects
  •  Alternative to painkillers
  •  May delay or avoid surgery
  •  Outpatient treatment without anesthesia

Possible side effects

Hyaluronic acid injections are usually well tolerated. Possible side effects:

  • Mild pain or feeling of pressure after the injection (1-2 days)
  • Swelling or redness at the injection site
  • Rare: joint effusion or inflammation
  • Very rare: Allergic reactions

Most side effects are mild and resolve within a few days.

When is the treatment not suitable?

Contraindications for hyaluronic acid injections:

  • Acute joint inflammation or infection
  • Known allergy to hyaluronic acid
  • Skin infections in the injection area
  • Severe coagulation disorders

Costs and reimbursement of costs

The costs vary depending on the preparation and number of injections. In our shop you will find all preparations at fair prices.

The reimbursement of costs by health insurance companies is regulated differently. Private health insurance companies usually cover the costs; for statutory health insurance companies this varies from case to case.

Study situation and evidence

Numerous studies prove the effectiveness of hyaluronic acid injections for osteoarthritis. Meta-analyses show significant improvements in pain and function, particularly in mild to moderate osteoarthritis.

The guidelines of various specialist societies recommend hyaluronic acid injections as a treatment option for knee osteoarthritis.

Combination with other therapies

Hyaluronic acid injections can be combined well with other treatments:

  • Physiotherapy: Supports the effect by building muscle
  • Weight reduction: Relieves the joints
  • Painkillers: Additionally possible if required
  • Orthopedic aids: Insoles, bandages etc.

Conclusion: Effective treatment option for osteoarthritis

Hyaluronic acid injections are an established, effective and well-tolerated treatment method for osteoarthritis. They can relieve pain, improve mobility and significantly increase quality of life.

Choosing the right preparation depends on individual factors. Ask your doctor for advice on which preparation is best for you.

You can find all hyaluronic acid preparations in our Joint syringe category.

Further information:

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