What is Ostenil Plus?
Ostenil Plus is a high-quality hyaluronic acid joint injection for the treatment of osteoarthritis and chronic joint pain. The crucial difference to conventional preparations: Ostenil Plus also contains Mannitol as an antioxidant, which stabilizes the hyaluronic acid and ensures a longer duration of action of 6-12 months.
With a concentration of 40 mg hyaluronic acid (20 mg/ml) in a 2 ml volume and a molecular weight of 1,200 kDa, Ostenil Plus is one of the most proven joint injections on the market.
💡 Special advantage
With mannitol as an antioxidant – better joint protection, longer duration of action and optimal tolerability.
What is mannitol and why is it important?
Mannitol is a natural antioxidant contained in Ostenil Plus and performs several important functions:
1. Protection against free radicals
Mannitol neutralizes free radicals in the joint, which occur more frequently in osteoarthritis and accelerate the breakdown of cartilage. This antioxidant protection slows the progression of the disease.
2. Stabilization of hyaluronic acid
By protecting against oxidative stress, hyaluronic acid remains active in the joint for longer. This results in an extended duration of action of 6-12 months.
3. Reducing inflammation
Mannitol has an anti-inflammatory effect and improves the tolerance of the injection. Swelling and irritation after treatment is less common.
4. Improved overall effect
The combination of hyaluronic acid and mannitol offers more comprehensive joint protection than pure hyaluronic acid preparations.
How does Ostenil Plus work for osteoarthritis?
Ostenil Plus develops its effect on several levels through the combination of hyaluronic acid and mannitol:
Improved joint lubrication
Hyaluronic acid acts as a natural lubricant and reduces friction between the joint surfaces. This leads to smoother movements and less wear and tear.
Shock absorption and cartilage protection
Ostenil Plus forms a protective layer on the cartilage and acts as a shock absorber. The cartilage is protected from further degradation and the load is distributed more evenly.
Anti-inflammatory
Both hyaluronic acid and mannitol inhibit inflammatory processes in the joint, which leads to a significant reduction in pain.
Antioxidant protection
Mannitol protects the joint from oxidative stress and sustainably slows down the progressive breakdown of cartilage.
Ostenil Plus vs. standard hyaluronic acid
Which joints is Ostenil Plus suitable for?
Ostenil Plus is used to treat osteoarthritis in the following joints:
- Knee joint (gonarthrosis) – most common application
- Hip joint (coxarthrosis)
- shoulder joint
- Ankle joint
- wrist
- Other large and small joints
Who benefits from Ostenil Plus?
Ostenil Plus is particularly suitable for patients with:
- Mild to moderate osteoarthritis
- Chronic joint pain despite conservative therapy
- Increased oxidative stress in the joint
- Desire for longer duration of action
- Restricted mobility in everyday life
- Insufficient effect of painkillers
- Desire for non-surgical treatment
- Bridging the gap until the planned operation
Professional use of Ostenil Plus for joint osteoarthritis
Treatment process: This is how the Ostenil Plus injection works
Before treatment
Your doctor will examine the affected joint and determine whether Ostenil Plus is suitable for you. In the case of acute inflammation or infection, treatment should be postponed.
Treatment regimen
Standard treatment usually includes:
- 1-3 injections at intervals of 1 week
- For mild osteoarthritis, only 1 injection is often sufficient
- For moderate osteoarthritis, 2-3 injections are recommended
- Your doctor adapts the regimen individually
During the injection
- Disinfection: The joint is thoroughly disinfected
- Anesthesia (optional): If necessary, local anesthesia of the injection site
- Injection: The hyaluronic acid is precisely injected into the joint space
- Duration: The entire treatment only takes a few minutes
After treatment
- Protection of the joint for 48 hours
- Avoid heavy exertion and exercise
- Light exercise is permitted and beneficial
- The first improvements are usually noticeable after 1-2 weeks
- Maximum effect after 4-8 weeks
Scientific evidence and study situation
The effectiveness of Ostenil Plus has been proven by numerous clinical studies. Patients report:
- Significant pain reduction by an average of 50-70%
- Improved joint function and mobility
- Longer duration of action through the addition of mannitol
- Increased quality of life in everyday life
- Reduced need for painkillers
- Delay in surgical interventions
Ostenil Plus is manufactured by TRB Chemedica and is clinically proven.
Frequently asked questions about Ostenil Plus
How long does Ostenil Plus last?
The effects usually last 6-12 months. Due to the mannitol it contains, the duration of action is longer than with standard hyaluronic acid preparations.
How many injections do I need?
Usually 1-3 injections 1 week apart. For mild osteoarthritis, one injection may be sufficient. Your doctor will advise you individually.
What is the difference from normal Ostenil?
Ostenil Plus also contains mannitol as an antioxidant. This offers better protection against oxidative stress, longer duration of action and improved tolerability.
Is the treatment painful?
The injection can be briefly uncomfortable, but is usually well tolerated. If desired, local anesthesia can be given. Mannitol makes swelling less common than with other preparations.
When does the effect occur?
The first improvements are usually noticeable after 1-2 weeks. The maximum effect occurs after 4-8 weeks.
Can I repeat the treatment?
Yes, the treatment can be repeated without any problems after 6-12 months. Many patients undergo regular treatment in order to remain permanently pain-free.
Does the health insurance company cover the costs?
The cost coverage varies depending on the health insurance company and individual situation. Talk to your doctor and your health insurance company about the options.
Are there any side effects?
Ostenil Plus is very well tolerated. Possible, mostly mild side effects include:
- Slight swelling or feeling of pressure in the joint (1-3 days)
- Temporary redness at the injection site
- Rare: joint effusion (usually self-limiting)
Technical data: Ostenil Plus 40 mg / 2 ml
Storage and shelf life
- Store at room temperature (below 25°C).
- Protect from direct sunlight
- Do not freeze
- Store in original packaging
- Note shelf life (see packaging)
Scope of delivery
- 1 pre-filled syringe of 2 ml (40 mg hyaluronic acid)
- 1 sterile injection cannula
- Package leaflet with detailed application information
- Certificate of Conformity
Order Ostenil Plus now
Premium hyaluronic acid with mannitol for 6-12 months effect
To the product →Conclusion: Why Ostenil Plus is the optimal choice for osteoarthritis
Ostenil Plus impresses with its unique combination of:
- ✅ Mannitol as an antioxidant for better joint protection
- ✅ Longer duration of action from 6-12 months
- ✅ High quality hyaluronic acid for optimal joint lubrication
- ✅ Reduced oxidative stress in the joint
- ✅ Excellent tolerance with minimal side effects
- ✅ Clinically proven from TRB Chemical
- ✅ Made in Germany according to the highest quality standards
If you suffer from osteoarthritis or chronic joint pain and are looking for an effective, non-surgical treatment option with antioxidant protection, Ostenil Plus is an excellent choice. Talk to your doctor about the options for Ostenil Plus treatment.
📦 Order Ostenil Plus now
Ostenil Plus 40 mg / 2 ml pre-filled syringe
✓ Available immediately
✓ Original from the manufacturer TRB Chemedica
✓ Made in Germany
✓ With mannitol as an antioxidant
✓ Includes sterile injection cannula