Ostenil Plus 40 mg 2 ml

Ostenil Plus 40 mg 2 ml – Premium Hyaluronic Acid Injection with Mannitol for Osteoarthritis Treatment

Ostenil Plus 40 mg is a high quality one Hyaluronic acid joint injection for intra-articular treatment of Osteoarthritis and degenerative joint diseases. The viscoelastic solution combines high molecular weight Hyaluronic acid (2.0-3.0 MDa) with the antioxidant Mannitol for optimal joint protection and long-term effect of 6-12 months.

Product features Ostenil Plus

• Active ingredient: 20 mg/ml sodium hyaluronate (40 mg per 2 ml pre-filled syringe)
• Molecular weight: 2.0-3.0 million Daltons – high molecular hyaluronic acid for maximum viscosity
• Mannitol supplement: Antioxidant to protect against free radicals and oxidative stress
• Sterile & pyrogen-free: CE-MDR certified according to the highest EU medical device standards
• Duration of action: 6-12 months for a single injection – long-lasting pain relief
• Pre-filled syringe: Ready to use for direct intra-articular use

Areas of application & indications

Ostenil Plus is used for the symptomatic treatment of degenerative and traumatic changes in the knee joint and other synovial joints Osteoarthritis used. Particularly suitable for:

• Gonarthrosis (knee osteoarthritis)
• Osteoarthritis in the hip, shoulder and ankle joints
• Degenerative joint diseases with pain and restricted movement
• Traumatic joint changes
• Patients with limited mobility due to joint wear

Mechanism of action – How does Ostenil Plus work?

Hyaluronic acid is a natural component of the synovial fluid (joint fluid) and plays a central role in joint function. With increasing age and osteoarthritis, the concentration and quality of the body's own hyaluronic acid decreases. Ostenil Plus works through:

• Improving viscosity: Increases the elasticity and lubrication of the synovial fluid
• Shock absorber function: Protects the cartilage from mechanical stress and abrasion
• Lubrication: Reduces friction between joint surfaces for more pain-free movement
• Cartilage protection: Protects cartilage tissue from further wear and tear
• Antioxidant effect: Mannitol neutralizes free radicals and reduces inflammatory oxidative stress in the joint

Advantages of Ostenil Plus over standard hyaluronic acid

The crucial difference: Ostenil Plus contains additionally Mannitol, a proven antioxidant. This addition offers:

• Protection against free radicals, which occur more frequently in osteoarthritis
• Reduction of oxidative stress in the joint space
• Extended duration of action of hyaluronic acid
• Improved tolerance

Application & dosage

Standard dosage: 1 injection of 2 ml per joint
Injection interval: Repeatable after 6-12 months if necessary
Administration: Intra-articular (directly into the joint) by medical professionals
Treatment cycle: As a rule, a single injection is sufficient for 6-12 months of effectiveness

Who is Ostenil Plus suitable for?

Ostenil Plus 40 mg is particularly suitable for:

• Patients with moderate to severe osteoarthritis
• People who want long-lasting pain relief
• Patients who cannot tolerate NSAIDs (non-steroidal anti-inflammatory drugs).
• Active people who want to maintain their mobility
• Clinics and practices with a focus on orthopedics and rheumatology

Scope of delivery

• 1 sterile pre-filled syringe with 2 ml Ostenil Plus (40 mg hyaluronic acid + mannitol)
• Detailed instructions for use
• CE declaration of conformity

Storage & Shelf Life

Store at room temperature (max. 25°C). Do not freeze. Protect from direct sunlight. Keep original packaging closed until use. Note the expiry date on the packaging.

Quality & Manufacturer

TRB Chemical AG – Quality manufacturer with over 30 years of experience in developing viscoelastic solutions for joint therapy. All products are manufactured in Europe according to the highest pharmaceutical standards.

Frequently asked questions about Ostenil Plus

How long does Ostenil Plus last?
The duration of action is usually 6-12 months after a single injection.

Is Ostenil Plus painful?
The injection is carried out by a healthcare professional and is usually well tolerated. Mild local reactions may occur.

Can Ostenil Plus be used repeatedly?
Yes, the treatment can be repeated after 6-12 months if necessary.

This product is intended for use by healthcare professionals only. Please note the instructions for use and specialist information.